The Vip nomenclature

Since the vegetatively expressed, and secreted, VIP proteins were first reported in the mid 1990s the rate of discovery of related toxins has increased in a similar fashion to that seen with the Cry toxins a decade previously. Given that each discovering lab are adopting their own naming systems for these toxins the idea was recently put forward that a nomenclature system, along the same lines used for the Cry and Cyt toxins, be adopted. On this web page we present the results of applying the Bt Cry toxin nomenclature analyses to the Vip and Vip-related toxins. The following table shows the proposed names for these toxins that result from such an analyses.

Vip1Aa1     Warren et al
1998
 US 5770696 June 1998 AB78  
Vip1Aa2 PS177C8 Mis AAR81088 Feitelson et al
1999
 US 6656908  Dec 2003 Bt PS177C8 WO9957282(A2,A3)  11Nov 1999
Vip1Aa3   GU992203 Xiumei Yu et al 2010   Bt 376  
.      
.
      
Vip1Ab1 Vip1Ab   Warren et al
1998
 US 5770696 June 1998 Btt  
.              
Vip1Ac1   HM439098 Xiumei Yu
2010
      
.              
Vip1Ba1 MB438 Mis (Blat 784D) AAR40886 Schnepf et al
2000
 US  6605701 Aug 2003 B lat MB438 WO0009697(A2,A3) 24Feb 2000
Vip1Ba2 ISP1B CAI43278 Van Rie 2005   B laterosporus  
.      
.
      
Vip1Bb1 PS31F2 Mis AAR40282 Feitelson et al
1999
 US 6656908  Dec 2003 Bt PS31F2 WO9957282(A2,A3)  11Nov 1999
.      
.
      
Vip1Bc1   HM485583 Sun Ming 2010      
.              
Vip1Ca1 Vip1Ac AAO86514 Shi et al
2003
 unpublished HD201  
.      
.
      
Vip1Da1 ISP1A CAI40767 Boets et al
2004
 US 6706860 Mar 2004    
.      
.
      
Vip2Aa1 Vip2Aa 1QS1A Warren et al
1998
 US 5770696 June 1998 AB78  
Vip2Aa2 PS177C8 War AAR81096 Feitelson et al
1999
 US 6656908  Dec 2003 Bt PS177C8 WO9957282(A2,A3)  11Nov 1999
Vip2Aa3   HM439097 Xiumei Yu 2010   Bt 376  
.      
.
      
Vip2Ab1 Vip2Ab   Warren et al
2000
 US 6066783 May 2000 Btt  
.      
.
      
Vip2Ac1 Vip2Ac AAO86513 Shi et al
2003
 unpublished HD201  
.      
.
      
Vip2Ad1 ISP2A CAI40768 Boets et al
2004
 US 6706860 Mar2004    
.              
Vip2Ae1   EF442245 Basu et al 2007 unpublished Bt  
Vip2Ae2   ACH42758 Roopadevi et al 2009 unpublished Bt HD8  
Vip2Ae3   HM439099 Xiumei Yu 2010 unpublished Bc 84  
.              
Vip2Af1   ACH42759 Roopadevi et al 2008 unpublished Bt HD525  
Vip2Af2   EU909204 Roopadevi et al 2008 unpublished    
.      
.
      
Vip2Ba1 MB438 War (Blat451D) AAR40887 Schnepf et al
1999
 US 6605701 Aug2003 B lat MB438 WO0009697(A2,A3) 24Feb 2000
Vip2Ba2 ISP2B CAI43279 Van Rie et al
2005
   B laterosporus  
.      
.
      
Vip2Bb1 PS31F2 War   Feitelson et al
1999
 US 6656908 Dec 2003 Bt PS31F2 WO9957282(A2,A3)  11Nov 1999
Vip2Bb2 HM485585   Sun et al 2010   Sbt106  
.      
.
      
Vip3Aa1 Vip3Aa AAC37036 Estruch et al
1996
 PNAS 93, 5389-5394 AB88  
Vip3Aa2 Vip3Ab AAC37037 Estruch et al
1996
 PNAS 93, 5389-5394 AB424  
Vip3Aa3 Vip3Ac   Estruch et al
2000
 US 6137033 Oct 2000    
Vip3Aa4 PS36A Sup AAR81079 Feitelson et al
1998
 US 6656908 Dec 2003 Bt PS36A WO9818932(A2,A3) 7 May 1998
Vip3Aa5 PS81F Sup AAR81080 Feitelson et al
1998
 US 6656908 Dec 2003 Bt PS81F WO9818932(A2,A3) 7 May 1998
Vip3Aa6 Jav90 Sup AAR81081 Feitelson et al
1998
 US 6656908 Dec 2003 Bt WO9818932(A2,A3) 7 May 1998
Vip3Aa7 Vip83 AAK95326 Cai et al
2001
 unpublished Bt YBT-833  
Vip3Aa8 Vip3A AAK97481 Loguercio et al
2001
 unpublished Bt HD125  
Vip3Aa9 VipS CAA76665 Selvapandiyan et al
2001
 unpublished Bt A13  
Vip3Aa10 Vip3V AAN60738 Doss et al
2002
 Protein Expr. Purif. 26, 82-88 Bt  
Vip3Aa11 Vip3A AAR36859 Liu et al
2003
 unpublished Bt C9  
Vip3Aa12 Vip3A-WB5 AAM22456 Wu and Guan
2003
 unpublished Bt  
Vip3Aa13 Vip3A AAL69542 Chen et al
2002
 Sheng Wu Gong Cheng Xue Bao 18, 687-692 Bt S184  
Vip3Aa14 Vip AAQ12340 Polumetla et al
2003
 unpublished Bt tolworthi  
Vip3Aa15 Vip3A AAP51131 Wu et al
2004
 unpublished Bt WB50  
Vip3Aa16 Vip3LB AAW65132 Mesrati et al 2005 FEMS Micro Lett 244, 353-358 Bt  
Vip3Aa17 Jav90   Feitelson et al 1999 US 6603063 Aug 2003 Javelin 1990 WO9957282(A2,A3)  11Nov 1999
Vip3Aa18   AAX49395 Cai and Xiao 2005 unpublished Bt 9816C  
Vip3Aa19 Vip3ALD DQ241674 Liu et al 2006 unpublished Bt AL  
Vip3Aa19 Vip3A-1 DQ539887 Hart et al 2006 unpublished    
Vip3Aa20 Vip3A-2 DQ539888 Hart et al 2006 unpublished    
Vip3Aa21 Vip ABD84410 Panbangred 2006 unpublished Bt aizawai  
Vip3Aa22 Vip3A-LS1 AAY41427 Lu et al 2005 unpublished Bt LS1  
Vip3Aa23 Vip3A-LS8 AAY41428 Lu et al 2005 unpublished Bt LS8  
Vip3Aa24   BI 880913 Song et al 2007 unpublished Bt WZ-7  
Vip3Aa25   EF608501 Hsieh et al 2007 unpublished    
Vip3Aa26   EU294496 Shen and Guo 2007 unpublished Bt TF9  
Vip3Aa27   EU332167 Shen and Guo 2007 unpublished Bt 16  
Vip3Aa28   FJ494817 Xiumei Yu 2008 unpublished Bt JF23-8  
Vip3Aa29   FJ626674 Xieumei et al 2009 unpublished Bt JF21-1  
Vip3Aa30   FJ626675 Xieumei et al 2009 unpublished MD2-1  
Vip3Aa31   FJ626676 Xieumei et al 2009 unpublished JF21-1  
Vip3Aa32   FJ626677 Xieumei et al 2009 unpublished MD2-1  
Vip3Aa33   GU073128 Diego Sauka 2009   Btk HD1  
Vip3Aa34   GU073129 Diego Sauka 2009   INTA TA24-6  
Vip3Aa35   GU733921 Audtho et al 2010 unpublished Bt M190  
Vip3Aa36   GU951510 Feng et al 2010      
Vip3Aa37   HM132041 Sauka et al 2010   Bt HD110  
Vip3Aa38   HM117632 Shu et al 2010      
Vip3Aa39   HM117631 Shu et al 2010      
Vip3Aa40   HM132042 Sauka et al 2010      
Vip3Aa41   HM132043 Sauka et al 2010      
Vip3Aa42   HQ587048 Marucci et al 2010      
Vip3Aa43   HQ594534 Marucci et al 2010      
Vip3Aa44   HQ650163 Kaur et al 2010   BCSC 4A6  
Vip3Aa45   JF710269 Palma et al 2011      
Vip3Aa46   JQ228436 Zhao Shiyuan 2011   Bt LB-73  
Vip3Aa47   JQ228435 Zhao Shiyuan 2011   Bt LS-10  
.      
.
      
Vip3Ab1 Vip3B AAR40284 Feitelson et al
1999
 US 6603063 Aug 2003 Bt KB59A4-6 WO9957282(A2,A3)  11Nov 1999
Vip3Ab2 Vip3D AAY88247 Feng and Shen 2006 unpublished Bt  
.      
.
      
Vip3Ac1 PS49C   Narva et al
.
 US application 20040128716    
.      
.
      
Vip3Ad1 PS158C2   Narva et al
.
 US application 20040128716    
Vip3Ad2 ISP3B CAI43276 Van Rie et al
2005
 unpublished Bt  
.      
.
      
Vip3Ae1 ISP3C CAI43277 Van Rie et al
2005
 unpublished Bt  
.      
.
      
Vip3Af1 ISP3A CAI43275 Van Rie et al
2005
 unpublished Bt  
Vip3Af2 Vip3C ADN08753 Syngenta
.
 WO 03/075655    
Vip3Af3   HM117634 Shu et al 2010      
.      
.
      
Vip3Ag1 Vip3B ADN08758 Syngenta
.
 WO 02/078437    
Vip3Ag2   FJ556803 Audtho et al 2010   Bt  
Vip3Ag3   HM117633 Shu et al 2010      
Vip3Ag4   HQ414237 Palma et al 2010      
Vip3Ag5   HQ542193 Marucci et al 2010      
Vip3Ag6   JQ397328 Palma et al 2011      
.      
.
      
Vip3Ah1 Vip3S DQ832323 Li and Shen 2006 unpublished Bt  
.              
Vip3Ba1   AAV70653 Rang et al 2004 unpublished    
Vip3Ba2   HM117635 Shu et al 2010      
.              
Vip3Bb1 Vip3Z ADN08760 Syngenta
.
 WO 03/075655    
Vip3Bb2   ABO30520 Beard et al 2007      
Vip3Bb3   ADI48120 Audtho et al 2010      
               
Vip3Ca1   HQ414239 Palma et al 2010      
Vip3Ca2   AEE98106 Hernandez et al 2010      
Vip3Ca3   HQ876489 Maeztu et al 2011      
Vip3Ca4   JN836992 Maeztu et al 2011      
               
Vip4Aa1   HM044666 Ming Sun et al 2010