Alzheimer's Disease and Frontotemporal Dementias

A Review with Particular Reference to Pin1 Protein

 

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Tauopathies

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Literature:   A-K ; L-Z ; subject area

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Compiled by: Julian Thorpe

 

Alzheimer's disease


General/Causes:    background / causes 

Hallmark lesions:    plaques / tangles

Genetic risk/susceptibility  factors: APP / presenilins / apoE

Cellular aspects: cytoskeleton

Biochemical aspects: molecular pathogenic inter-relationships / 'AD cascade' / kinases / phosphatases / cellcycle events / apoptosis / oxidative stress

AD models: transgenic mice / pig / rabbit / rat / Caenorhabditis elegans / Drosophila / cells

Electron Microscopy: our research on Pin1 and AD / tangles / general in AD / PHF-tau / beta-amyloid

Information: Literature A-K / Literature L-Z / Literature by subject areas / other sources 

Links: links to other sites


The Involvement of Pin1 Protein in Alzheimer's Disease

Some related tauopathies (N.B. this part is under construction at present): general / corticobasal degeneration / Down's syndrome / FTDP-17 / Pick's disease / progressive supranuclear palsy

N.B. We have recently been awarded a 3-Year  Project Grant from

to study Pin1 protein's involvement in the tauopathies

***** (See the University Press Release about our Wellcome Project Grant) *****