Literature: A-K ; L-Z ; subject area
Compiled by: Julian Thorpe
Corticobasal Degeneration (CBD)
N.B. This page is in the initial phases of construction, so I suggest you follow the external link below for more on this disease.
(external site links in italics )
 | See: The 'Institut National de la Sante et de la Recherche Medical' website for more detail on CBD, the NINDS CBD Information Page and the 'We Move' site ('the Internet's most comprehensive resource for movement disorder information ') |
| Type: CBD is a sporadic, adult-onset neurodegenerative disease and belonging to the frontotemporal dementia (FTD) group. It is a movement disorder but there is also mild-to-moderate cognitive impairment. |
| Regions affected: Cerebral cortex , deep cerebellar nuclei and substantia nigra . |
| Tau pathology: Neuronal: intracytoplasmic PHF-like filaments and straight tubules. Glial : intracytoplasmic PHF-like filaments and straight tubules; plaques in astrocytes ; 'coiled body' inclusions in astrocyte and oligodendrocyte white matter. Neuropil threads : extensive throughout grey and white matter. |
Arai, T, Ikeda, K, Akiyama, H, Tsuchiya, K, Yagishita, S, Takamatsu, J (2001) Intracellular processing of aggregated tan differs between corticobasal degeneration and progressive supranuclear palsy. NEUROREPORT 12: 935-938
Arai, T, Ikeda, K, Akiyama, H, Shikamoto, Y, Tsuchiya, K, Yagishita, S, Beach, T, Rogers, J, Schwab, C, McGeer, PL (2001) Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy. ACTA NEUROPATHOLOGICA 101: 167-17
Arai, T, Ikeda, K, Akiyama, H, Tsuchiya, K, Iritani, S,
Ishiguro, K, Yagishita, S, Oda, T, Odawara, T, Iseki, E (2003)
Different immunoreactivities of the microtubule-binding region of tau and its
molecular basis in brains from patients with Alzheimer's disease, Pick's
disease, progressive supranuclear palsy and corticobasal degeneration. ACTA
NEUROPATHOLOGICA 105: 489-498
Berry, RW, Sweet, AP, Clark, FA, Lagalwar, S, Lapin, BR, Wang, T, Topgi, S, Guillozet-Bongaarts, AL, Cochran, EJ, Bigio, EH, Binder, LI (2004) Tau epitope display in progressive supranuclear palsy and corticobasal degeneration. JOURNAL OF NEUROCYTOLOGY 33: 287-295
Cordato, NJ, Halliday, GM, McCann, H, Davies, L, Williamson, P, Fulham, M, Morris, JGL (2001) Corticobasal syndrome with tau pathology. MOVEMENT DISORDERS 16: 656-667
de Silva, R, Hardy, J, Crook, J, Khan, N, Graham, EA,
Morris, CM, Wood, NW, Lees, AJ (2002) The tau locus is not significantly associated with
pathologically confirmed sporadic Parkinson's disease
Dickson,
DW, Bergeron, C, Chin, SS, Duyckaerts, C, Horoupian, D, Ikeda, K, Jellinger, K,
Lantos, PL, Lippa, CF, Mirra, SS, Tabaton, M, Vonsattel, JP, Wakabayashi, K,
Litvan, I (2002)
Ferrer, I, Barrachina, M, Puig, B (2002) Glycogen synthase kinase-3 is associated with neuronal
and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's
disease, progressive supranuclear palsy and corticobasal degeneration
Ferrer, I, Blanco, R, Carmona, M, Ribera, R, Goutan, E, Puig, B, Rey, MJ, Cardozo, A, Vinals, F and Ribalta, T (2001) Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. BRAIN PATHOLOGY 11: 144-158
Forman, MS, Zhukareva, V, Bergeron, C, Chin, SSM, Grossman, M, Clark, C, Lee, VMY, Trojanowski, JQ (2002) Signature tau neuropathology in gray and white matter of corticobasal degeneration. AMERICAN JOURNAL OF PATHOLOGY 160: 2045-2053
Graham, NL, Bak, TH, Hodges, JR (2003)
Corticobasal degeneration as a cognitive disorder. MOVEMENT DISORDERS 18:
1224-1232
Hattori, M, Hashizume, Y, Yoshida, M, Iwasaki, Y,
Hishikawa, N, Ueda, R, Ojika, K (2003)
Distribution of astrocytic plaques in the corticobasal degeneration brain and
comparison with tuft-shaped astrocytes in the progressive supranuclear palsy
brain. ACTA NEUROPATHOLOGICA 106: 143-149
Houlden, H, Baker, M, Morris, HR, MacDonald, N, Pickering-Brown, S, Adamson, J, Lees, AJ, Rossor, MN, Quinn, NP, Kertesz, A, Khan, MN, Hardy, J, Lantos, PL, George-Hyslop, PS, Munoz, DG, Mann, D, Lang, AE, Bergeron, C, Bigio, EH, Litvan, I, Bhatia, KP, Dickson, D, Wood, NW, Hutton, M (2001) Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype. NEUROLOGY 56: 1702-1706
Ikeda, K, Akiyama, H, Arai, T, Tsuchiya, K (2002) Pick-body-like inclusions in corticobasal degeneration differ from Pick bodies in Pick's disease. ACTA NEUROPATHOLOGICA 103: 115-118
Ishizawa, K, Dickson, DW (2001) Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 60: 647-657
Kasashima, S, Oda, Y (2003) Cholinergic neuronal loss in the basal forebrain and mesopontine tegmentum of progressive supranuclear palsy and corticobasal degeneration. ACTA NEUROPATHOLOGICA 105: 117-124
Katsuse, O, Iseki, E, Arai, T, Akiyama, H, Togo, T, Uchikado, H, Kato, M, de Silva, R, Lees, A, Kosaka, K (2003) 4-repeat tauopathy sharing pathological and biochemical features of corticobasal degeneration and progressive supranuclear palsy. ACTA NEUROPATHOLOGICA 106: 251-260
Kertesz, A (2003)
Pick complex: An integrative approach to frontotemporal dementia - Primary
progressive aphasia, corticobasal degeneration, and progressive supranuclear
palsy. NEUROLOGIST 9: 311-317
Kleiner-Fisman, G, Black, SE, Lang, AE (2003) Neurodegenerative disease and the evolution of art: The effects of presumed corticobasal degeneration in a professional artist. MOVEMENT DISORDERS 18: 294-302
Monza, D, Ciano, C, Scaioli, V, Soliveri, P, Carella,
F, Avanzini, G, Girotti, F (2003) Neurophysiological features in relation to
clinical signs in clinically diagnosed corticobasal degeneration. NEUROLOGICAL
SCIENCES 24: 16-23
Pharr, V, Uttl, B, Stark, M, Litvan, I, Fantie, B, Grafman, J (2001) Comparison of apraxia in corticobasal degeneration and progressive supranuclear palsy. NEUROLOGY 56: 957-963
Piao, YS, Hayashi, S, Wakabayashi, K, Kakita, A, Aida, I, Yamada, M, Takahashi, H (2002) Cerebellar cortical tau pathology in progressive supranuclear palsy and corticobasal degeneration. ACTA NEUROPATHOLOGICA 103: 469-474
Sobrido, MJ, Abu-Khalil, A, Weintraub, S, Johnson, N,
Quinn, B, Cummings, JL, Mesulam, MM, Geschwind, DH (2003)
Possible association of the tau H1/H1 genotype with primary progressive aphasia.
NEUROLOGY 60: 862-864
Stover, NP, Watts, RL (2001) Corticobasal degeneration. SEMINARS IN NEUROLOGY 21: 49-58
Uchihara, T, Nakamura, A, Yamazaki, M and Mori, O (2000) Tau-positive neurons in corticobasal degeneration and Alzheimer's disease - distinction by thiazin red and silver impregnations. ACTA NEUROPATHOLOGICA 100: 385-389
Zhukareva, V, Sundarraj, S, Mann, D, Sjogren, M, Blenow, K, Clark, CM, McKeel, DW, Goate, A, Lippa, CF, Vonsattel, JP, Growdon, JH, Trojanowski, JQ, Lee, VMY (2003) Selective reduction of soluble Tau proteins in sporadic and familial frontotemporal dementias: an international follow-up study. ACTA NEUROPATHOLOGICA 105: 469-476
Back to Top