| ‘The
tempo and mode of molecular evolution’. I am interested in
variation in the rate of molecular evolution and how it correlates
with biological factors such as life history traits. I have recently
been investigating the effect of body size and metabolic rate on
substitution rates in invertebrates. Observations of a body size
effect in vertebrates have raised hopes that rate variation might
be predictable, potentially allowing a ‘corrected’ clock.
However there is no evidence of such an effect in 5 invertebrate
phyla (Arthopoda, Mollusca, Echinodermata, Platyhelminthes and Annelida). |
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Thomas,
J.A., Welch, J.J., Woolfit, M. and Bromham, L. (2006) ‘No
universal molecular clock in invertebrates but rate variation does
not scale with body size” PNAS. PDF
E. Fontanillas, E., Thomas, J.A. and Bromham, L. (2006) ‘Could
fast diversification rates or small body sizes increase molecular
substitution rates during the Cambrian "explosion"?’
(publication in prep.).
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